In its biggest challenge of the season, Northwestern lost handedly to No. 16 Notre Dame Wednesday in a 110-52 defeat. The Wildcats (2-1, 0-0 Big Ten) got out to an 8-0 lead capped by junior guard Hailey Weaver’s fast-break layup, forcing the Fighting Irish (2-1, 0-0 ACC) to take an early timeout just over two…
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